Diphtheria Immunization

Diphtheria Immunization *

AT the beginning of the twentieth century diphtheria occupied a unique position in contrast to other infectious diseases. Its symptoms and course were well known and accurately described, the causal organism definitely recognized, and a specific remedy was available for its treatment, yet in spite of this wealth of scientific knowledge the control and prevention of the disease had proved a comp...

Studies on Diphtheria- Tetanus, combined immunization in children in some elementary school of Teheran

Passive Antibacterial Immunization in Conjunctival Diphtheria in Guinea Pigs.

In a previous paper (Hirose et al., 1962) it was reported that guinea pigs highly immunized against a bacterial suspension of Corynebacterium diphtheriae resisted to a challenge by the conjunctival method (Murata et al., 1959) with a toxinogenic virulent strain without even traces of antitoxic immunity, while a passive transfer of the immunity failed. The reason for this failure may have been d...

Role of health communications in Russia's diphtheria immunization program.

As part of a broader program in health communication assistance, project staff from Basic Support for Institutionalizing Child Survival worked with staff from Russia's oblast (regional) public health agencies to design and implement communication activities supporting local diphtheria immunization efforts. Because aggressive community outreach efforts and strong administrative sanctions had alr...

Successful immunization with a totally synthetic diphtheria vaccine.

Three peptides corresponding to fragments of diphtheria toxin have been synthesized. They include the previously described tetradecapeptide and two structural analogs, the hexadecapeptide and the octadecapeptide. Conjugates of these peptides to proteins or a synthetic carrier have induced in guinea pig protection against the dermonecrotic activity of diphtheria toxin. All of the conjugates were...